Cancer Research Trials

Advancing Cancer Research at New York Oncology Hematology (NYOH)

For over 30 years, NYOH has been a leader in cancer research. Our patients have helped bring more than 100 FDA-approved cancer treatments to life by joining clinical trials. With the region’s largest cancer research program, we offer access to groundbreaking therapies—often before they’re available anywhere else.

What Are Clinical Trials?

Clinical trials are research studies involving volunteer participants who help evaluate new cancer treatments. These studies are essential to advancing cancer care, testing everything from the effectiveness of new drugs to innovative ways to manage side effects.

NYOH conducts Phase I through Phase IV clinical trials, covering all major solid tumors, blood cancers, and supportive care therapies. Our involvement in every phase of research ensures patients have access to the full spectrum of emerging treatment options.

Our Commitment to Cancer Research

At NYOH, you have access to cutting-edge cancer clinical trials without the need to travel to a large city. Our team is committed to bringing the latest, most promising treatments right here to your community so that you can stay close to home and with the people who support you. We're focused on advancing cancer care through safe, ethical research while making sure you receive the personalized, compassionate care you deserve.

Making a Difference—Together

More than 3,000 NYOH patients have participated in clinical trials over the past 20 years, helping to approve over 50 new cancer therapies. Their participation continues to shape the future of cancer treatment, offering hope to thousands more.

Cancer Research That Changed Lives — And Still Does

At New York Oncology Hematology (NYOH), we’re proud to be part of the breakthroughs that shape the future of cancer treatment. Many of the medications we now use in everyday cancer care were once tested in clinical trials right here at NYOH — giving our patients early access to cutting-edge therapies while helping bring life-saving treatments to the world.

Here are just some of the now FDA-approved drugs that NYOH helped bring to market through clinical research:
Chemotherapy Agents

Medications that attack fast-growing cancer cells directly.

 

Abraxane

Alimta

Camptosar

Doxil

Eloxatin

Gemzar

Halaven

Hycamtin

Ixempra

Onivyde

Taxotere

Trodelvy

Xeloda

Yondelis

 

Targeted Therapies

Treatments that block cancer’s specific growth drivers, often with fewer side effects.

 

Afinitor

Arimidex

Aromasin

Avastin

Cyramza

Erbitux

Faslodex

Herceptin

Inlyta

Iressa

Kadcyla

Nexavar

Sutent

Talzenna

Tarceva

Tykerb

Vectibix

Verzenio

Votrient

 

Immunotherapy

Treatments that block cancer’s specific growth drivers, often with fewer side effects.

 

Adcetris

Bavencio

Gazyva

Keytruda

Opdivo

Provenge

Rituxan

Tecentriq

 

Supportive & Bone-Strengthening Treatments

Helping patients tolerate treatment and protect healthy cells.

 

Aranesp

Neulasta

Neupogen

Zometa

 

 

Blood & Bone Marrow Cancer Therapies

Medications used in leukemia, lymphoma, and related conditions.

 

Vidaza

 Sprycel

Tasigna

 

Prostate Cancer Therapies

Hormone-targeting and immune-based treatments.

 

Erleada

Provenge

 

 

Inside the NYOH Clinical Research Program

Our expert team of oncologists and research professionals leads clinical trials across every NYOH location. We partner with top pharmaceutical companies to bring the latest treatments to our community. Each trial is closely monitored for safety and effectiveness.

 

A Principal Investigator, a physician responsible for the design, conduct, and safety of the trial, oversees each study. The NYOH Research Oversight Committee, led by Dr. Lawrence Garbo (Chair) and Dr. Karen Tedesco (Vice Chair), ensures scientific integrity and regulatory compliance across all research activities.

 

To learn more about a study or to refer an eligible patient, please contact our research department.

Lawrence Garbo, MD

Hematology & General Cancer Studies

Karen Tedesco, MD

Breast Studies

Courtney Bellomo, MD

Hematology Studies

Rufus Collea, MD

Breast Studies

Makenzi Evangelist, MD

Lung and Sarcoma Studies

Rehu George, MD

Hematology Studies

Mihir Raval, MD

Hematology Studies

Rahul Ravilla, MD

GU Studies (Prostate, Bladder, Renal Cell)

Howard Scholossberg, MD

General Cancer studies

Stephen Wrzesinski, MD, PhD

Lung & Melanoma Studies

Qin Zen, MD

Hematology and Solid tumor studies

Clinical Trials at NYOH – Frequently Asked Questions (FAQ)

What is a clinical trial?

A clinical trial is a research study that involves people. It helps determine whether new cancer treatments are safe and effective after they’ve been tested in labs and on animals. Clinical trials are essential for improving how we prevent, detect, and treat cancer.

Why does NYOH participate in clinical trials?

NYOH takes part in clinical research to:

  • Advance cancer care with better treatments
  • Improve the quality of life and survival for patients
  • Offer patients access to promising therapies not yet available to the public
Why are clinical trials important?

Clinical trials are the foundation of modern cancer treatment. Every standard therapy used today was first studied in a trial. NYOH has helped gain FDA approval for over 100 cancer treatments. Clinical trials contribute to:

  • Longer survival rates
  • Lower recurrence of some cancers
  • Fewer side effects and better quality of life
  • New options for hard-to-treat cancers

 

How many cancer patients join clinical trials?

Only about 3% of adult cancer patients enroll in clinical trials. Increasing participation helps researchers find better treatments faster. NYOH offers the most comprehensive cancer clinical trial program in the region.

What types of clinical trials are available?

NYOH offers a variety of clinical trials, including:

  • Treatment trials: Test new cancer drugs or combinations
  • Prevention trials: Explore ways to prevent cancer or its return
  • Screening trials: Improve early cancer detection methods
  • Quality-of-life trials: Help reduce side effects and improve comfort
What is a clinical trial protocol?

A protocol is the detailed plan for a clinical trial. It outlines the purpose, treatment steps, number of participants, and how information is collected. All protocols are reviewed by qualified researchers and approved by an Institutional Review Board (IRB).

What does the Institutional Review Board (IRB) do?

The IRB protects participants by ensuring:

  • Risks are minimized, and benefits are reasonable
  • Participants are selected fairly
  • Informed consent is obtained and documented
  • Patient safety, privacy, and data confidentiality are maintained
Why should I consider joining a clinical trial at NYOH?
  • You may gain access to innovative new treatments
  • You’ll receive close monitoring and personalized care
  • You’ll help advance cancer research and benefit future patients